技術摘要(英)
This technical product using tetracalcium phosphate (TTCP) as matrix, and mixed with monocalcium phosphate monobasic (MCPM) in a specific proportion, and then combined with collagen. Freeze-drying molding technology was then utilized to produce flexible products. The prepared polymer/biomedical ceramic scaffold can be self-hardening after being combined with phosphate ion solution to complete the final application form of the product, which is suitable for filling the function of complex bone defect types. In addition, sub-micron process technology and ion induction technology which is applied in the product could improve the bone repair effect. In a series of effect verification results, it was found that the hardened ceramic scaffold had good mechanical strength, biocompatibility and excellent bone cell differentiation/mineralization effect at the initial stage. In view of this, the polymer/bioceramic scaffold has excellent biomedical potential and can be used as the key to break through the bottleneck of the traditional grafts in orthopaedic clinics.